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Gene Ontology Browser
Term Detail
GO term:GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity
Synonym: GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity
Synonym: GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity
Synonym: GDP-mannose-oligosaccharide-lipid mannosyltransferase activity
Synonym: glycolipid 2-alpha-mannosyltransferase activity
Synonym: guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity
Synonym: oligosaccharide-lipid mannosyltransferase activity
GO id:GO:0004377
Definition:Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
Number of paths to term: 2

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring glycosyl groups
                                        is-atransferase activity, transferring hexosyl groups
                                                is-amannosyltransferase activity
                                                        is-aalpha-1,2-mannosyltransferase activity
                                                                is-adol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
                                                                is-adol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity
                                                                is-aGDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [GO:0004377] (1 genes, 1 annotations)


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-atransferase activity
                                is-atransferase activity, transferring glycosyl groups
                                        is-atransferase activity, transferring hexosyl groups
                                                is-amannosyltransferase activity
                                                        is-aglycolipid mannosyltransferase activity
                                                                is-aGDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
                                                                is-aGDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity [GO:0004377] (1 genes, 1 annotations)
                                                                is-aglycolipid 6-alpha-mannosyltransferase activity


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory