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Term Detail
GO term:antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
Synonym: endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-dependent
Synonym: TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway
Synonym: TAP-dependent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway
GO id:GO:0002489
Definition:The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
Number of paths to term: 4

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aantigen processing and presentation
                                is-aantigen processing and presentation of endogenous antigen
                                        is-aantigen processing and presentation of endogenous peptide antigen
                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib
                                                        is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489] (3 genes, 4 annotations)
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aantigen processing and presentation
                                is-aantigen processing and presentation of peptide antigen
                                        is-aantigen processing and presentation of endogenous peptide antigen
                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib
                                                        is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489] (3 genes, 4 annotations)
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aantigen processing and presentation
                                is-aantigen processing and presentation of peptide antigen
                                        is-aantigen processing and presentation of peptide antigen via MHC class Ib
                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib
                                                        is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489] (3 genes, 4 annotations)
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aantigen processing and presentation
                                is-aantigen processing and presentation via MHC class Ib
                                        is-aantigen processing and presentation of peptide antigen via MHC class Ib
                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib
                                                        is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [GO:0002489] (3 genes, 4 annotations)
                                                                is-aantigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory