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Gene Ontology Browser
Term Detail
GO term:alpha-beta T cell activation involved in immune response
Synonym: alpha-beta T cell activation during immune response
Synonym: alpha-beta T-cell activation during immune response
Synonym: alpha-beta T lymphocyte activation during immune response
Synonym: alpha-beta T-lymphocyte activation during immune response
GO id:GO:0002287
Definition:The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
Number of paths to term: 17

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-acell activation involved in immune response
                                                is-aleukocyte activation involved in immune response
                                                        is-alymphocyte activation involved in immune response
                                                                is-aT cell activation involved in immune response
                                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                                is-aNK T cell activation involved in immune response +
                                                                        is-acytotoxic T cell degranulation +
                                                                        is-agamma-delta T cell activation involved in immune response +
                                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-aleukocyte activation involved in immune response
                                                        is-alymphocyte activation involved in immune response
                                                                is-aT cell activation involved in immune response
                                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                                is-aNK T cell activation involved in immune response +
                                                                        is-acytotoxic T cell degranulation +
                                                                        is-agamma-delta T cell activation involved in immune response +
                                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-alymphocyte activation
                                                        is-alymphocyte activation involved in immune response
                                                                is-aT cell activation involved in immune response
                                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                                is-aNK T cell activation involved in immune response +
                                                                        is-acytotoxic T cell degranulation +
                                                                        is-agamma-delta T cell activation involved in immune response +
                                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-alymphocyte activation
                                                        is-aT cell activation
                                                                is-aalpha-beta T cell activation
                                                                        is-aalpha-beta T cell activation by superantigen
                                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                                is-aNK T cell activation involved in immune response +
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-aalpha-beta T cell proliferation +
                                                                        is-aCD4-positive, alpha-beta T cell activation +
                                                                        is-aCD8-positive, alpha-beta T cell activation +
                                                                        negatively-regulatesnegative regulation of alpha-beta T cell activation +
                                                                        is-aNK T cell activation +
                                                                        positively-regulatespositive regulation of alpha-beta T cell activation +
                                                                        regulatesregulation of alpha-beta T cell activation +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-alymphocyte activation
                                                        is-aT cell activation
                                                                is-aT cell activation involved in immune response
                                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                                is-aNK T cell activation involved in immune response +
                                                                        is-acytotoxic T cell degranulation +
                                                                        is-agamma-delta T cell activation involved in immune response +
                                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aimmune effector process
                                is-acell activation involved in immune response
                                        is-aleukocyte activation involved in immune response
                                                is-alymphocyte activation involved in immune response
                                                        is-aT cell activation involved in immune response
                                                                is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                        is-aalpha-beta T cell differentiation involved in immune response +
                                                                        is-aalpha-beta T cell proliferation involved in immune response +
                                                                        is-aNK T cell activation involved in immune response +
                                                                is-acytotoxic T cell degranulation +
                                                                is-agamma-delta T cell activation involved in immune response +
                                                                is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                is-aT cell differentiation involved in immune response +
                                                                is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aimmune response
                                part-ofcell activation involved in immune response
                                        is-aleukocyte activation involved in immune response
                                                is-alymphocyte activation involved in immune response
                                                        is-aT cell activation involved in immune response
                                                                is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                        is-aalpha-beta T cell differentiation involved in immune response +
                                                                        is-aalpha-beta T cell proliferation involved in immune response +
                                                                        is-aNK T cell activation involved in immune response +
                                                                is-acytotoxic T cell degranulation +
                                                                is-agamma-delta T cell activation involved in immune response +
                                                                is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                is-aT cell differentiation involved in immune response +
                                                                is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aleukocyte activation
                                is-aleukocyte activation involved in immune response
                                        is-alymphocyte activation involved in immune response
                                                is-aT cell activation involved in immune response
                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                is-aNK T cell activation involved in immune response +
                                                        is-acytotoxic T cell degranulation +
                                                        is-agamma-delta T cell activation involved in immune response +
                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                        is-aT cell differentiation involved in immune response +
                                                        is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aleukocyte activation
                                is-alymphocyte activation
                                        is-alymphocyte activation involved in immune response
                                                is-aT cell activation involved in immune response
                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                is-aNK T cell activation involved in immune response +
                                                        is-acytotoxic T cell degranulation +
                                                        is-agamma-delta T cell activation involved in immune response +
                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                        is-aT cell differentiation involved in immune response +
                                                        is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aleukocyte activation
                                is-alymphocyte activation
                                        is-aT cell activation
                                                is-aalpha-beta T cell activation
                                                        is-aalpha-beta T cell activation by superantigen
                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                is-aNK T cell activation involved in immune response +
                                                        is-aalpha-beta T cell differentiation +
                                                        is-aalpha-beta T cell proliferation +
                                                        is-aCD4-positive, alpha-beta T cell activation +
                                                        is-aCD8-positive, alpha-beta T cell activation +
                                                        negatively-regulatesnegative regulation of alpha-beta T cell activation +
                                                        is-aNK T cell activation +
                                                        positively-regulatespositive regulation of alpha-beta T cell activation +
                                                        regulatesregulation of alpha-beta T cell activation +


Gene_Ontology
        is-abiological_process
                is-aimmune system process
                        is-aleukocyte activation
                                is-alymphocyte activation
                                        is-aT cell activation
                                                is-aT cell activation involved in immune response
                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                is-aNK T cell activation involved in immune response +
                                                        is-acytotoxic T cell degranulation +
                                                        is-agamma-delta T cell activation involved in immune response +
                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                        is-aT cell differentiation involved in immune response +
                                                        is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-aresponse to stimulus
                        is-aimmune response
                                part-ofcell activation involved in immune response
                                        is-aleukocyte activation involved in immune response
                                                is-alymphocyte activation involved in immune response
                                                        is-aT cell activation involved in immune response
                                                                is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                        is-aalpha-beta T cell differentiation involved in immune response +
                                                                        is-aalpha-beta T cell proliferation involved in immune response +
                                                                        is-aNK T cell activation involved in immune response +
                                                                is-acytotoxic T cell degranulation +
                                                                is-agamma-delta T cell activation involved in immune response +
                                                                is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                is-aT cell differentiation involved in immune response +
                                                                is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-acell activation involved in immune response
                                                is-aleukocyte activation involved in immune response
                                                        is-alymphocyte activation involved in immune response
                                                                is-aT cell activation involved in immune response
                                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                                is-aNK T cell activation involved in immune response +
                                                                        is-acytotoxic T cell degranulation +
                                                                        is-agamma-delta T cell activation involved in immune response +
                                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-aleukocyte activation involved in immune response
                                                        is-alymphocyte activation involved in immune response
                                                                is-aT cell activation involved in immune response
                                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                                is-aNK T cell activation involved in immune response +
                                                                        is-acytotoxic T cell degranulation +
                                                                        is-agamma-delta T cell activation involved in immune response +
                                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-alymphocyte activation
                                                        is-alymphocyte activation involved in immune response
                                                                is-aT cell activation involved in immune response
                                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                                is-aNK T cell activation involved in immune response +
                                                                        is-acytotoxic T cell degranulation +
                                                                        is-agamma-delta T cell activation involved in immune response +
                                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        is-aT cell proliferation involved in immune response +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-alymphocyte activation
                                                        is-aT cell activation
                                                                is-aalpha-beta T cell activation
                                                                        is-aalpha-beta T cell activation by superantigen
                                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                                is-aNK T cell activation involved in immune response +
                                                                        is-aalpha-beta T cell differentiation +
                                                                        is-aalpha-beta T cell proliferation +
                                                                        is-aCD4-positive, alpha-beta T cell activation +
                                                                        is-aCD8-positive, alpha-beta T cell activation +
                                                                        negatively-regulatesnegative regulation of alpha-beta T cell activation +
                                                                        is-aNK T cell activation +
                                                                        positively-regulatespositive regulation of alpha-beta T cell activation +
                                                                        regulatesregulation of alpha-beta T cell activation +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell activation
                                        is-aleukocyte activation
                                                is-alymphocyte activation
                                                        is-aT cell activation
                                                                is-aT cell activation involved in immune response
                                                                        is-aalpha-beta T cell activation involved in immune response [GO:0002287] (40 genes, 57 annotations)
                                                                                is-aalpha-beta T cell differentiation involved in immune response +
                                                                                is-aalpha-beta T cell proliferation involved in immune response +
                                                                                is-aNK T cell activation involved in immune response +
                                                                        is-acytotoxic T cell degranulation +
                                                                        is-agamma-delta T cell activation involved in immune response +
                                                                        is-aT cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell +
                                                                        is-aT cell differentiation involved in immune response +
                                                                        is-aT cell proliferation involved in immune response +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory