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Gene Ontology Browser
Term Detail
GO term:cell cycle checkpoint
Synonym: G1/S checkpoint
Synonym: G1/S transition checkpoint
Synonym: G2/M checkpoint
Synonym: G2/M transition checkpoint
GO id:GO:0000075
Definition:A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.
CommentsNote that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here.
Number of paths to term: 37

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-anegative regulation of biological process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cell cycle process
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-anegative regulation of cellular process
                                                is-anegative regulation of cell cycle process
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-anegative regulation of cell cycle process
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-abiological regulation
                        is-aregulation of biological process
                                is-aregulation of cellular process
                                        is-aregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-aregulation of cell cycle phase transition
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        negatively-regulatesnegative regulation of cellular process
                                is-anegative regulation of cell cycle process
                                        is-anegative regulation of cell cycle phase transition
                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                        is-aDNA integrity checkpoint +
                                                        is-ameiotic cell cycle checkpoint +
                                                        is-amitotic cell cycle checkpoint +
                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                        regulatesregulation of cell cycle checkpoint +
                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                        is-aspindle checkpoint +
                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of cell cycle process
                                                is-anegative regulation of cell cycle phase transition
                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                is-aDNA integrity checkpoint +
                                                                is-ameiotic cell cycle checkpoint +
                                                                is-amitotic cell cycle checkpoint +
                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                regulatesregulation of cell cycle checkpoint +
                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                is-aspindle checkpoint +
                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell cycle
                                        is-aregulation of cell cycle process
                                                is-anegative regulation of cell cycle process
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        regulatesregulation of cellular process
                                is-aregulation of cell cycle
                                        is-aregulation of cell cycle process
                                                is-aregulation of cell cycle phase transition
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle phase transition
                                                        negatively-regulatesnegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle phase transition
                                                        regulatesregulation of cell cycle phase transition
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                negatively-regulatesnegative regulation of cell cycle process
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                regulatesregulation of cell cycle process
                                                        is-anegative regulation of cell cycle process
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                regulatesregulation of cell cycle process
                                                        is-aregulation of cell cycle phase transition
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        regulatesregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-anegative regulation of cell cycle process
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        regulatesregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-aregulation of cell cycle phase transition
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle phase transition
                                                negatively-regulatesnegative regulation of cell cycle phase transition
                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                is-aDNA integrity checkpoint +
                                                                is-ameiotic cell cycle checkpoint +
                                                                is-amitotic cell cycle checkpoint +
                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                regulatesregulation of cell cycle checkpoint +
                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                is-aspindle checkpoint +
                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle phase transition
                                                regulatesregulation of cell cycle phase transition
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        negatively-regulatesnegative regulation of cell cycle process
                                                is-anegative regulation of cell cycle phase transition
                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                is-aDNA integrity checkpoint +
                                                                is-ameiotic cell cycle checkpoint +
                                                                is-amitotic cell cycle checkpoint +
                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                regulatesregulation of cell cycle checkpoint +
                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                is-aspindle checkpoint +
                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        regulatesregulation of cell cycle process
                                                is-anegative regulation of cell cycle process
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        regulatesregulation of cell cycle process
                                                is-aregulation of cell cycle phase transition
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                negatively-regulatesnegative regulation of biological process
                        is-anegative regulation of cellular process
                                is-anegative regulation of cell cycle process
                                        is-anegative regulation of cell cycle phase transition
                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                        is-aDNA integrity checkpoint +
                                                        is-ameiotic cell cycle checkpoint +
                                                        is-amitotic cell cycle checkpoint +
                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                        regulatesregulation of cell cycle checkpoint +
                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                        is-aspindle checkpoint +
                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-anegative regulation of biological process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of cell cycle process
                                                is-anegative regulation of cell cycle phase transition
                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                is-aDNA integrity checkpoint +
                                                                is-ameiotic cell cycle checkpoint +
                                                                is-amitotic cell cycle checkpoint +
                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                regulatesregulation of cell cycle checkpoint +
                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                is-aspindle checkpoint +
                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-anegative regulation of cellular process
                                        is-anegative regulation of cell cycle process
                                                is-anegative regulation of cell cycle phase transition
                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                is-aDNA integrity checkpoint +
                                                                is-ameiotic cell cycle checkpoint +
                                                                is-amitotic cell cycle checkpoint +
                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                regulatesregulation of cell cycle checkpoint +
                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                is-aspindle checkpoint +
                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of cell cycle
                                        is-aregulation of cell cycle process
                                                is-anegative regulation of cell cycle process
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                regulatesregulation of biological process
                        is-aregulation of cellular process
                                is-aregulation of cell cycle
                                        is-aregulation of cell cycle process
                                                is-aregulation of cell cycle phase transition
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle phase transition
                                                        negatively-regulatesnegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                is-acell cycle phase transition
                                                        regulatesregulation of cell cycle phase transition
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                negatively-regulatesnegative regulation of cell cycle process
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                regulatesregulation of cell cycle process
                                                        is-anegative regulation of cell cycle process
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        part-ofcell cycle process
                                                regulatesregulation of cell cycle process
                                                        is-aregulation of cell cycle phase transition
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        regulatesregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-anegative regulation of cell cycle process
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle
                                        regulatesregulation of cell cycle
                                                is-aregulation of cell cycle process
                                                        is-aregulation of cell cycle phase transition
                                                                is-anegative regulation of cell cycle phase transition
                                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                                is-aDNA integrity checkpoint +
                                                                                is-ameiotic cell cycle checkpoint +
                                                                                is-amitotic cell cycle checkpoint +
                                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                                regulatesregulation of cell cycle checkpoint +
                                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                                is-aspindle checkpoint +
                                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle phase transition
                                                negatively-regulatesnegative regulation of cell cycle phase transition
                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                is-aDNA integrity checkpoint +
                                                                is-ameiotic cell cycle checkpoint +
                                                                is-amitotic cell cycle checkpoint +
                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                regulatesregulation of cell cycle checkpoint +
                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                is-aspindle checkpoint +
                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        is-acell cycle phase transition
                                                regulatesregulation of cell cycle phase transition
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        negatively-regulatesnegative regulation of cell cycle process
                                                is-anegative regulation of cell cycle phase transition
                                                        is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                is-aDNA integrity checkpoint +
                                                                is-ameiotic cell cycle checkpoint +
                                                                is-amitotic cell cycle checkpoint +
                                                                negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                positively-regulatespositive regulation of cell cycle checkpoint +
                                                                regulatesregulation of cell cycle checkpoint +
                                                                part-ofsignal transduction involved in cell cycle checkpoint +
                                                                is-aspindle checkpoint +
                                                        is-anegative regulation of meiotic cell cycle phase transition +
                                                        is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                        is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        regulatesregulation of cell cycle process
                                                is-anegative regulation of cell cycle process
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acell cycle process
                                        regulatesregulation of cell cycle process
                                                is-aregulation of cell cycle phase transition
                                                        is-anegative regulation of cell cycle phase transition
                                                                is-acell cycle checkpoint [GO:0000075] (139 genes, 181 annotations)
                                                                        part-ofdetection of stimulus involved in cell cycle checkpoint +
                                                                        is-aDNA integrity checkpoint +
                                                                        is-ameiotic cell cycle checkpoint +
                                                                        is-amitotic cell cycle checkpoint +
                                                                        negatively-regulatesnegative regulation of cell cycle checkpoint +
                                                                        positively-regulatespositive regulation of cell cycle checkpoint +
                                                                        regulatesregulation of cell cycle checkpoint +
                                                                        part-ofsignal transduction involved in cell cycle checkpoint +
                                                                        is-aspindle checkpoint +
                                                                is-anegative regulation of meiotic cell cycle phase transition +
                                                                is-anegative regulation of metaphase/anaphase transition of cell cycle +
                                                                is-anegative regulation of mitotic cell cycle phase transition +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/05/2013
MGI 5.13
The Jackson Laboratory