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Eomestm4.1(icre)Rob - Extraembryonic Component
Recombinase Activity Detail
Allele Information
Allele:
Eomestm4.1(icre)Rob
eomesodermin; targeted mutation 3.1, Elizabeth J Robertson
Driver: Eomes
Type: Targeted (Recombinase)
Synonym: EomesiCre
Molecular description: A targeting vector introduced the coding sequence for improved Cre recombinase (iCre) coding sequence followed by a polyA cassette and a loxP-flanked neomycin-resistance cassette was introduced into the exon 1 start site of the Eomes gene, resulting in deletion of about 500 base pairs of the 5' coding region. Correctly targeted ES cells were transiently transfected with a plasmid encoding cre to remove the neomycin cassette. The resulting cells were used to generate germline chimeras.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Eomestm4.1(icre)Rob activity also observed in:
embryo-other, mesenchyme
Tissue Information
Extraembryonic Component Other recombinase alleles with activity in Extraembryonic Component tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory