Gt(ROSA)26Sor<tm1(BEST1-cre/ERT2)Vold> - Hemolymphoid System Recombinase Activity Detail MGI Mouse

Gt(ROSA)26Sor^{tm1(BEST1-cre/ERT2)Vold} - Hemolymphoid System
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Gt(ROSA)26Sor^{tm1(BEST1-cre/ERT2)Vold}
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Douglas Vollrath

Driver: BEST1
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Rosa26^{BEST1-CreERT2}

Molecular description:

The allele was created to have the human BEST1 promoter/enhancer regions directing the expression of a CreER(T2) fusion gene. The targeting vector contained, from 5' to 3', the human BEST1 promoter (nucleotides -585 to +38), followed by a CreER(T2) fusion gene, and an SV40 a polyA cassette. The plasmid was pronuclear injected into C57BL/6J(attPx3) zygotes along with phiC31 integrase mRNA. The resulting founder mice were bred with C57BL/6J for germline transmission.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Gt(ROSA)26Sor^{tm1(BEST1-cre/ERT2)Vold} activity also observed in:
head, reproductive system, sensory organs

Recombinase Activity

Click heading to re-sort table.

Assays Genotypic Background Result Notes

References

All for this allele:

1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23