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Tg(Aldh1l1-cre/ERT2)1Khakh - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(Aldh1l1-cre/ERT2)1Khakh
transgene insertion 1, Baljit Khakh 		Driver: Aldh1l1
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Aldh1l1-Cre/ERT2 BAC
Molecular description: The transgene contains the entire containing the entire aldehyde dehydrogenase 1 family member L1 locus (Aldh1l1), as well as ~49 kbp 5' (centromeric) flanking region and ~130 kbp 3' (telomeric) flanking region from BAC RP23-7M9. Using homologous recombination/BAC recombineering, a CreER cDNA sequence followed by an SV40 polyadenylation signal was inserted into exon 1 of the BAC Aldh1l1 gene immediately preceding the translation initiation codon. No other loci on the BAC were altered. Two founder lines with germline transmission are generated. Founder line #1 was established and characterized.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Aldh1l1-cre/ERT2)1Khakh activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 61 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory