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Tg(Cck-cre,-lacZ)1Mini - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cck-cre,-lacZ)1Mini
transgene insertion 1, Liliana Minichiello 		Driver: Cck
Type: Transgenic (Recombinase, Reporter)
Synonym: BAC-Cck-Cre, Cck-cre
Molecular description: A BAC (RP23-26B6) containing the Cck gene was modified by ET recombination so that a cassette composed of a hybrid intron, a cre recombinase gene, an internal ribosomal entry site (IRES), a beta-galactosidase gene (lacZ), and a neomycin/kanamycin resistance marker was inserted into the first ATG of the first coding exon (exon 2). The neo/kan marker was removed using flp recombinase. The purified construct was injected into the pronuclei of (CBA x C57BL/6) hybrid oocytes.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cck-cre,-lacZ)1Mini activity also observed in:
head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:210229 Fig. 1 J:210229 Fig. 5 J:210229 Fig. 6 J:210229 Fig. S1 J:210229 Fig. S2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory