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Tg(hs218-Ccre,-lacZ)1Fawa - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(hs218-Ccre,-lacZ)1Fawa
transgene insertion 1, Fan Wang 		Driver: hs218
Type: Transgenic (Recombinase)
Synonym: CreC218
Molecular description: The C-terminal fragment of cre recombinase (aa 60-343) fused to the intein-C peptide fragment (36 C terminal amino acids) of the DnaE split intein sequence was cloned into a vector containing the human enhancer 218 sequence (hs218) and an Hsp68 minimal promoter and lacZ reporter. The final construct included an IRES sequence separating the lacZ gene and Ccre-intein-C. Injection of the linearized construct into pronuclei was performed to generated transgenic founders. Line numbers were not identified in the publication.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(hs218-Ccre,-lacZ)1Fawa activity also observed in:
nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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J:207270 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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04/09/2024
MGI 6.23 		The Jackson Laboratory