Hdc<tm1.1(icre)Wwis> - Nervous System Recombinase Activity Detail MGI Mouse

Hdc^{tm1.1(icre)Wwis} - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Hdc^{tm1.1(icre)Wwis}
histidine decarboxylase; targeted mutation 1.1, William Wisden

Driver: Hdc
Type: Targeted (Recombinase)

Synonym:

HDC-Cre

Molecular description:

A targeting vector was generated to insert an improved IRES2i site, a humanized cre open reading frame and an FRT-flanked neo selection cassette into exon 12 of histidine decarboxylase between the stop codon and polyadenylation sequence, by homologous recombination in ES cells. Chimeras were produced by ES cell injection into C57BL/6J blastocysts. The resulting line was bred with Flp deleter mice to remove the neo cassette.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Hdc^{tm1.1(icre)Wwis} activity also observed in:
head

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Images

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J:188103 Fig. 3

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

9 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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