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Cfap126tm1.1(icre)Heli - Alimentary System
Recombinase Activity Detail
Allele Information
cilia and flagella associated protein 126; targeted mutation 1.1, Heiko Lickert
Driver: Cfap126
Type: Targeted (Recombinase)
Synonym: 1700009P17Riktm1.1(icre)Heli, FltpT2AiCre
Molecular description: A vector was constructed to insert a strept/FLAG-tandem affinity tag (SF-TAG) followed by a T2A peptide sequence (from Thosea asigna virus) and the codon-improved cre recombinase (icre) sequence into exon 6 of the 1700009P17Rik gene (called Flattop; Fltp). An Frt-flanked PGK-neo sequence followed cre in the construct. The targeting vector was introduced into IDG3.2 ES cells for homologous recombination. Southern blotting showed that recombination occurred on the C57BL/6J allele. After germline transmission was established, mice were crossed to Flpe-expressing line to remove the neo cassette.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Cfap126tm1.1(icre)Heli activity also observed in:
cardiovascular system, embryo-other, mesenchyme, nervous system, respiratory system, sensory organs
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory