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Tg(Slco1c1-icre/ERT2)1Mrks - Reproductive System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Slco1c1-icre/ERT2)1Mrks
transgene insertion 1, Markus Schwaninger
Driver: Slco1c1
Type: Transgenic (Inducible, Recombinase)
Inducer: induced by tamoxifen
Synonym: Slco1c1-CreERT2
Molecular description: A bacterial artificial chromosome (BAC; RP24-85B20) was modified by homologous recombination to insert a codon-improved cre (icre) fused to a mutated human estrogen receptor ligand binding domain (ERT2). The targeting construct, which also contained an Frt-flanked ampicillin resistance cassette, was electroporated into bacterial cells containing the BAC. Cells with recombinant BAC clones were induced with L-arabinose to induce Flp recombinase expression to excise the resistance marker. The BAC was isolated, purified and injected into mouse pronuclei to obtain transgenic animals. No founder information was available so line 1 was entered.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Slco1c1-icre/ERT2)1Mrks activity also observed in:
cardiovascular system, nervous system
Tissue Information
Reproductive System Other recombinase alleles with activity in Reproductive System tissues:
Images
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J:179050 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory