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Ccktm1.1(cre)Zjh - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Ccktm1.1(cre)Zjh
cholecystokinin; targeted mutation 1.1, Z Josh Huang
Driver: Cck
Type: Targeted (Recombinase)
Synonym: Cck-IRES-Cre
Molecular description: A targeting vector was designed to insert an internal ribosome entry site (IRES), a cre recombinase sequence, a polyA sequence, and an frt-flanked neo cassette into the 3' untranslated region (after the translational termination site) of the cholecystokinin locus (Cck). This construct was electroporated into C57BL/6;129 embryonic stem (ES) cells. Correctly targeted ES cells were injected into recipient blastocysts. Chimeric males were bred with Actin-FLPe females (on a C57BL/6 congenic background) to achieve germline transmission and to remove the neo selection cassette. The resulting pups harboring the cre targeted mutation were selected. These Cck-IRES-Cre mice were subsequently bred together for several generations (and the FLPe transgene was removed).
Collection: Neuroscience Blueprint cre
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Ccktm1.1(cre)Zjh activity also observed in:
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Images
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Fig. Cck Embryo 1 E15.5
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Fig. Cck Embryo 2 E15.5
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Fig. Cck Embryo 3 E15.5
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Fig. Cck Embryo 4 E15.5
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Fig. Cck Embryo 5 E15.5
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Fig. Cck Embryo 6 E15.5
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Fig. Cck Mammary P56
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Fig. Cck Skin P56
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Fig. Cck Skin P7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory