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Ccktm1.1(cre)Zjh - Alimentary System
Recombinase Activity Detail
Allele Information
cholecystokinin; targeted mutation 1.1, Z Josh Huang
Driver: Cck
Type: Targeted (Recombinase)
Synonym: Cck-IRES-Cre
Molecular description: A targeting vector was designed to insert an internal ribosome entry site (IRES), a cre recombinase sequence, a polyA sequence, and an frt-flanked neo cassette into the 3' untranslated region (after the translational termination site) of the cholecystokinin locus (Cck). This construct was electroporated into C57BL/6;129 embryonic stem (ES) cells. Correctly targeted ES cells were injected into recipient blastocysts. Chimeric males were bred with Actin-FLPe females (on a C57BL/6 congenic background) to achieve germline transmission and to remove the neo selection cassette. The resulting pups harboring the cre targeted mutation were selected. These Cck-IRES-Cre mice were subsequently bred together for several generations (and the FLPe transgene was removed).
Collection: Neuroscience Blueprint cre
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Ccktm1.1(cre)Zjh activity also observed in:
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
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Fig. Cck Gut P7
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Fig. Cck Intestine P56
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Fig. Cck Pancreas (female) P7
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Fig. Cck Pancreas (male) P7
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Fig. Cck Pancreas P56
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Fig. Cck Stomach P56
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory