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Foxl2tm1(GFP/cre/ERT2)Pzg - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Foxl2tm1(GFP/cre/ERT2)Pzg
forkhead box L2; targeted mutation 1, Pumin Zhang
Driver: Foxl2
Type: Targeted (Inducible, Recombinase, Reporter)
Inducer: tamoxifen
Synonym: FoxL2-GCE, Foxl2tm1(GFP/cre/ERT2)Zhang
Molecular description: A targeting vector containing GFP-Cre/ERT2 cassette (GCE) and FRT site flanked Kanamycin/neomycin selection cassette was used to disrupt the exon containing the ATG translation start-site. The construct was electroporated into 129P2/OlaHsd derived E14Tg2a.4 embryonic stem (ES) cells. No green fluorescence was detected by direct fluorescence microscopy; however, immunohistochemical analysis revealed GFP expression in E18.5 embryos.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Foxl2tm1(GFP/cre/ERT2)Pzg activity also observed in:
alimentary system, endocrine system, head, nervous system, reproductive system
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory