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Tg(S100b-EGFP/cre/ERT2)22Amc - Limbs
Recombinase Activity Detail
Allele Information
transgene insertion 22, Andrew P McMahon
Driver: S100b
Type: Transgenic (Inducible, Recombinase, Reporter)
Inducer: tamoxifen
Synonym: S100b-GCE
Molecular description: A targeting construct containing the eGFPCreERT2 (GCE) cassette and FRT site flanked Kanamycin/neomycin selection cassette was inserted into the consensus start ATG codon of the gene in a BAC (RP23-213P2). The PGK-Neo/Kan cassette was removed by transient Flpe-recombinase expression. The resulting BAC transgene was microinjected into (C57BL/6 x DBA)F1 donor eggs. Founder line 22 was subsequently established. GFP fluorescence is not detectable by fluorescent microscope examination of whole embryos, bones or neural tube sagittal slices from embryos aged 15.5dpc. Tamoxifen induced cre recombinase activity is detected in a subset of the GFP immunoreactive-positive cells in bone.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(S100b-EGFP/cre/ERT2)22Amc activity also observed in:
nervous system, skeletal system
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
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J:159099 Fig. 2 S100b
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory