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Etv1tm1.1(cre/ERT2)Zjh - Nervous System
Recombinase Activity Detail
Allele Information
ets variant 1; targeted mutation 1.1, Z Josh Huang
Driver: Etv1
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: ER81-CreER, Er81-CreER-KI, ER81-CreERT2, Etv1-CreER, Etv1-CreERT2
Molecular description: A targeting vector was designed to insert a Cre/ERT2 fusion gene , an SV40 polyA signal, and an frt-flanked neo cassette into the initiation codon of the ets variant gene 1 locus (Etv1). This construct was electroporated into C57BL/6-derived embryonic stem (ES) cells. Correctly targeted ES cells were injected into recipient blastocysts and chimeric mice were bred with white C57BL/6 mice (harboring the Tyrc-2J mutation) to originate the colony. Mutant mice were bred with Actin-FLPe mice (on a C57BL/6 congenic background) to remove the neo selection cassette.
Collection: Neuroscience Blueprint cre
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Etv1tm1.1(cre/ERT2)Zjh activity also observed in:
alimentary system, cardiovascular system
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
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Fig. Etv1 Adult CB
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Fig. Etv1 Adult DRG
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Fig. Evt1 Adult Cerebral cortex
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Fig. Evt1 Adult HT
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory