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Ssttm2.1(cre)Zjh - Renal And Urinary System
Recombinase Activity Detail
Allele Information
somatostatin; targeted mutation 2.1, Z Josh Huang
Driver: Sst
Type: Targeted (Recombinase)
Synonym: SOM-iCre, SOM-IRES-Cre, Sst-iCre, Sst-IRES-Cre
Molecular description: A targeting vector was designed to insert an internal ribosome entry site (IRES), a Cre recombinase sequence, a polyA sequence, and an frt-flanked neo cassette into the 3' untranslated region (after the translational termination site) of the somatostatin locus (Sst). This construct was electroporated into C57BL/6;129 embryonic stem (ES) cells. Correctly targeted ES cells were injected into recipient blastocysts. Chimeric males were bred with Actin-FLPe females (on a C57BL/6 congenic background) to achieve germline transmission and to remove the neo selection cassette.
Collection: Neuroscience Blueprint cre
Find mice (IMSR): Mouse Strains: 3 strains available       Cell Lines: 0 lines available
Additional Tissues: Ssttm2.1(cre)Zjh activity also observed in:
Tissue Information
Renal And Urinary System Other recombinase alleles with activity in Renal And Urinary System tissues:
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J:184579 Full image
Fig. Sst Bladder P56
J:184579 Full image
Fig. Sst Kidney P56
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 34 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory