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Airetm3(cre)Mmat - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Airetm3(cre)Mmat
autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); targeted mutation 3, Mitsuru Matsumoto
Driver: Aire
Type: Targeted (Recombinase)
Synonym: Aire/Cre KI
Molecular description: A cre recombinase-floxed neomycin resistance cassette was inserted into exon 1 of the Aire gene, such that expression was under control of the endogenous Aire promoter. The floxed neo cassette was spontaneously deleted, likely as a result of autonomous expression of cre from the Aire locus during early embryogenesis and/or spermatogenesis.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Airetm3(cre)Mmat activity also observed in:
hemolymphoid system, integumental system, nervous system
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:160217 Fig. S3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory