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Tg(S100b-cre)20Ito - Nervous System
Recombinase Activity Detail
Allele Information
transgene insertion 20, Shigeyoshi Itohara
Driver: S100b
Type: Transgenic (Recombinase)
Synonym: S100b-Cre, Tg20
Molecular description: The nls-cre (nuclear localization sequence-cre) polyA cassette was inserted immediately upstream of the translation initiation site in an 11.7 kb S100b promoter-containing genomic sequence (-5387/+6357). This targeting construct was microinjected into pronuclei of fertilized C57BL/6 embryos. Six lines were generated, four of which showed similar recombination patterns in the adult brain when crossed to transgenic reporter mice. Line 20 (Tg20) displayed no recombination in the heart, lung, kidney, spleen, skeletal muscle, and blood vessel and partial recombination in skin and liver.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(S100b-cre)20Ito activity also observed in:
cardiovascular system, integumental system
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory