Acan<tm1(cre/ERT2)Crm> - Nervous System Recombinase Activity Detail MGI Mouse

Acan^{tm1(cre/ERT2)Crm} - Nervous System
Recombinase Activity Detail

Allele Information | Images | Recombinase Activity | References

Allele Information

Allele:

Acan^{tm1(cre/ERT2)Crm}
aggrecan; targeted mutation 1, Benoit de Crombrugghe

Driver: Acan
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Agc1^{CreERT2), Agc1, Agc^Cre, Agc^{tm(IRES-CreERT-Neo-pgk}}

Molecular description:

IRES-cre/ERT2 and an FRT-flanked PGK-neo selection cassette (in reverse orientation to the target gene) was inserted into the 3' UTR of the Aggrecan gene by homologous recombination in G4 ES cells. The line was established by breeding to C57BL/6 mice. The neo cassette was not removed.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Acan^{tm1(cre/ERT2)Crm} activity also observed in:

embryo-other, head, limbs, mesenchyme ...(more)

Images

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J:155982 Fig. 3

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

61 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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