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Tg(Nes-cre/ERT2)1Kag - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Nes-cre/ERT2)1Kag
transgene insertion 1, Ryoichiro Kageyama
Driver: Nes
Type: Transgenic (Inducible, Recombinase)
Inducer: induced by tamoxifen
Synonym: Nestin-CreER.line1
Molecular description: This transgene consists of a 5.8 kb fragment of the rat Nes promoter and a 1.8 kb fragment of the second intron of Nes driving expression of a tamoxifen-inducible form of cre recombinase followed by an SV40 poly A sequence. Three lines were created (lines 1, 4 and 5-1) with differing levels of activity (high, medium and low, respectively) and leakiness (high, low and none, respectively).
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:110145 Fig. 2 J:110145 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory