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Tg(Pomc-cre)5Brn - Endocrine System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pomc-cre)5Brn
transgene insertion 5, Anton Berns
Driver: Pomc
Type: Transgenic (Recombinase)
Synonym: Tg(Pomc1-cre)1Brn, Tg(Pomc-cre)1Brn, Tg(PomcCre)5Brn
Molecular description: This transgene contains 706 base pairs of 5' flanking sequence containing the promoter of the rat pro-opiomelanocortin gene followed by the coding sequence for Cre recombinase with an amino-terminal nuclear localization signal (nlsCre), a synthetic intron, and SV40 splice and polyadenylation signals. Progeny of mice bearing this transgene crossed to lacZ Cre reporter mice exhibited large numbers of X-gal staining cells in the intermediate lobe and lesser staining in the anterior lobe of the pituitary gland.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
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J:80158 Fig. 7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory