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Tg(KRT5-cre/ERT2)1Blh - Respiratory System
Recombinase Activity Detail
Allele Information
Allele:
Tg(KRT5-cre/ERT2)1Blh
transgene insertion 1, Brigid L Hogan
Driver: KRT5
Type: Transgenic (Inducible, Recombinase)
Inducer: induced by tamoxifen
Synonym: KRT5-CreERT2
Molecular description: The 6-kb human keratin 5 (KRT5) promoter drives a cre/ERT2 cassette. The cre/ERT2 is flanked by an intron and a polyadenylation sequence from the pCI mammalian expression vector. The construct was injected into fertilized zygotes. 11 founder lines were obtained, and 1 line that gave robust recombination in tracheal basal cells was propagated and maintained on a C57BL/6 x C3H background.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Respiratory System Other recombinase alleles with activity in Respiratory System tissues:
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J:152012 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory