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Tg(Lhx6-icre)1Kess - Nervous System
Recombinase Activity Detail
Allele Information
transgene insertion 1, Nicoletta Kessaris
Driver: Lhx6
Type: Transgenic (Recombinase)
Synonym: Lhx6Cre, Lhx6-Cre, Tg(Lhx6-cre)1Kess
Molecular description: Homologous recombination in bacteria was used to modify a genomic BAC containing the Lhx6 locus (RP24-384G1). An icre (improved cre) coding sequence was fused to the ATG of Lhx6 in exon 1 using a PCR-based approach. An SV40 polyA was inserted downstream of iCre. The construct was designed to delete the coding sequence of exon 1, as well as the first 80 bp from the first intron. Mice were generated by pronuclear injection of the construct into fertilized oocytes. No line number is given.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory