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Sox17tm1(icre)Heli - Liver And Biliary System
Recombinase Activity Detail
Allele Information
SRY (sex determining region Y)-box 17; targeted mutation 1, Heiko Lickert
Driver: Sox17
Type: Targeted (Recombinase)
Synonym: Sox17iCre, Sox17iCredeltaneo, Sox17tm1(icre)Lic
Molecular description: A targeting vector containing a mini gene locus with a codon improved cre recombinase cDNA with a translational stop codo, splice donor site, artificial intron and an exon encoding the SV40 polyadenylation signal followed by an FRT-flanked PGK-neo cassette in the opposite orientation was introduced into exon 1 of Sox17 by homologous recombination in TBV2 ES cells. Germline chimeras were generated and the neo cassette was excised by crossing these with Flpe mice.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Sox17tm1(icre)Heli activity also observed in:
Tissue Information
Liver And Biliary System Other recombinase alleles with activity in Liver And Biliary System tissues:
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J:150862 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory