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Et(cre/ERT2)837Rdav - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Et(cre/ERT2)837Rdav
enhancer trap 837, Ron Davis 		Driver: Et(cre/ERT2)837Rdav
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym:
Molecular description: An enhancer trap transgenic approach was used to generate these mice. The longtk-cre:ERT2-SV40pA transgene was designed with the long form of the thymidine kinase minimal (TK) promoter driving a cre-ERT2 fusion gene (cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain). The SV40 polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 837 was established on a C57BL/6J genetic background.
Collection: Neuroscience Blueprint cre
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Et(cre/ERT2)837Rdav activity also observed in:
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Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory