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Tg(Hspa2-cre)1Eddy - Skeletal System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Hspa2-cre)1Eddy
transgene insertion 1, Edward M Eddy
Driver: Hspa2
Type: Transgenic (Recombinase)
Synonym: Hspa2-cre, Hspa2-cre line 54
Molecular description: The Hspa2-Cre transgene was designed with (from 5' to 3') a 53 bp mouse Acrv1 (acrosomal vesicle protein 1 [SP-10]) insulator element, a promoter element from the mouse Hspa2 locus (heat shock protein 2 [Hsp70-2]); containing the ATG start site and 892 bp of immediately upstream sequence), a 275 bp fragment of the cre gene, the bovine growth hormone 3' UTR and polyA sequence, and another 53 bp mouse Acrv1 insulator element. This transgene was injected into C57BL/6 pronuclear stage embryos. Expression of Cre recombinase is directed to the developing male germ cells.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Hspa2-cre)1Eddy activity also observed in:
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
Images
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J:184579 Full image
Fig. Hspa2 Embryo E15.5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory