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Allele Information
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Allele:
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Tg(Hspa2-cre)1Eddy
transgene insertion 1, Edward M Eddy
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Driver: Hspa2
Type: Transgenic (Cre/Flp)
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Synonym:
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Hspa2-cre, Hspa2-cre line 54
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Molecular description:
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The Hspa2-Cre transgene was designed with (from 5' to 3') a 53 bp mouse Acrv1 (acrosomal vesicle protein 1 [SP-10]) insulator element, a promoter element from the mouse Hspa2 locus (heat shock protein 2 [Hsp70-2]); containing the ATG start site and 892 bp of immediately upstream sequence), a 275 bp fragment of the cre gene, the bovine growth hormone 3' UTR and polyA sequence, and another 53 bp mouse Acrv1 insulator element. This transgene was injected into C57BL/6 pronuclear stage embryos. Expression of Cre recombinase is directed to the developing male germ cells.
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Find mice (IMSR):
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Mouse Strains:
1 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Hspa2-cre)1Eddy activity also observed in:
adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
cavities and their linings,
embryo-other,
endocrine system,
hemolymphoid system,
integumental system,
limbs,
liver and biliary system,
muscle,
nervous system,
renal and urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system,
tail
(less)
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Tissue Information
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Mesenchyme
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Other recombinase alleles with activity in Mesenchyme tissues:
1700009P17Riktm1.1(icre)Heli,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Crhtm1(cre)Zjh,
Dmbx1tm3(cre)Aoh,
Emx1tm1(cre)Krj,
Emx2tm2(cre)Sia,
En1tm2(cre)Wrst,
Foxa2tm2.1(cre/Esr1*)Moon,
Gad2tm2(cre)Zjh,
Gt(ROSA)26Sortm1(FLP1)Dym,
HhatTg(TFAP2A-cre)1Will,
Krt19tm1(cre)Mmt,
Meox1tm1(cre)Jpa,
Myf5tm1.1(cre)Mrc,
Myf5tm1(cre)Mrc,
Myf5tm3(cre)Sor,
Myf6tm1(cre)Mrc,
Myf6tm2(cre)Mrc,
Myocdtm1(cre)Jomm,
Myod1tm2.1(icre)Glh,
Nkx2-5tm2(cre)Rph,
Nkx3-2tm3.1(cre)Tlu,
Nkx3-2tm4.1(cre)Tlu,
Notch1tm3(cre)Rko,
Osr1tm1(EGFP/cre/ERT2)Amc,
Osr2tm2(cre)Jian,
Pax3tm1(cre)Joe,
Six1tm1(cre,ALPP)Xli,
Sox17tm1(icre)Heli,
Ssttm2.1(cre)Zjh,
Tg(ACTA1-cre)79Jme,
Tg(ACTA1-rtTA,tetO-cre)102Monk,
Tg(ACTC1-cre)1Miwa,
Tg(Adipoq-cre)1Evdr,
Tg(Amy2-cre)1Herr,
Tg(CD2-cre)4Kio,
Tg(Cdh5-cre)7Mlia,
Tg(CMV-cre)1And,
Tg(Col1a2-cre/ERT)7Cpd,
Tg(Col2a1-cre)10Amc,
Tg(Col2a1-cre)15Amc,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre)1Bhr,
Tg(COL2A1-cre)1Wag,
Tg(Col2a1-cre)3Amc,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Csrp1-cre)1Sjc,
Tg(DBH-cre)6-8Koba,
Tg(DBH-cre)9-9Koba,
Tg(Dll1-cre)1Gos,
Tg(Dll1-cre)33Dchp,
Tg(dlx6a-cre)1Mekk,
Tg(DMRT1-cre)1Svs,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp4-cre)1Rev,
Tgfb3tm1(cre)Vk,
Tg(Foxa3-cre)1Khk,
Tg(Frzb-cre)1Tylz,
Tg(GATA5-cre)1Krc,
Tg(Grik4-cre)G32-4Stl,
Tg(Hes7-cre)1Kag,
Tg(Hoxa2-cre)1Dym,
Tg(Hoxb3-cre)1Pkht,
Tg(Hoxb6-cre)A5Mku,
Tg(Hoxb6-cre)C33Mku,
Tg(Ins2-cre)25Mgn,
Tg(Kdr-cre)15962Brei,
Tg(Leftb-cre)1Hmd,
Tg(Mef2c-cre)1Blk,
Tg(Mpz-cre)94Imeg,
Tg(Myl1-cre)13Nros,
Tg(MYOD1-cre)M23Glh,
Tg(Myog-cre)1Eno,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Nes-cre)1Wmz,
Tg(Nkx2-1-cre)2Sand,
Tg(Osr1-cre)4Mrt,
Tg(P0-Cre)1Gth,
Tg(Pax2-cre)10Shwl,
Tg(Pax3-cre)2Joe,
Tg(Pf4-cre)Q3Rsko,
Tg(Pitx3-cre/ERT2)1Ydq,
Tg(Prrx1-cre)1Cjt,
Tg(Prrx1-cre/ERT2)1Mlgn,
Tg(Sim1-cre)1Lowl,
Tg(Smad7-cre)1Sjc,
Tg(Tagln-cre)1Her,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tbx18-icre)1Fech,
Tg(Tbx1-cre)1Joe,
Tg(T-cre)1Gos,
Tg(T-cre)1Lwd,
Tg(Thy1-cre)1Vln,
Tg(Tie1-cre)9Ref,
Tg(Tlx2-cre)#Mori,
Tg(Wnt1-cre)11Rth,
Tg(Wnt1-cre/ERT)1Alj,
Twist2tm1.1(cre)Dor,
Twist2tm1(cre)Dor
(less)
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Images
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J:184579
Fig. Hspa2 Embryo 2 E10.5
J:184579
Fig. Hspa2 Embryo 3 E10.5
J:184579
Fig. Hspa2 Embryo 4 E10.5
J:184579
Fig. Hspa2 Embryo E10.5
J:184579
Fig. Hspa2 Embryo E15.5
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools