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Tg(Cdh5-cre)1Nmoc - Mesenchyme
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cdh5-cre)1Nmoc
transgene insertion 1, Naoki Mochizuki 		Driver: Cdh5
Type: Transgenic (Recombinase)
Synonym: VE-cad-Cre
Molecular description: A 2.5 kb fragment of the Cdh5 promoter region followed by the cre recombinase cDNA and the SV40 polyadenylation signal was inserted into the pBluescriptSKII plasmid. The transgene fragment was excised and microinjected into C57BL/6J fertilized oocytes. Three founder lines were obtained, All three showed no differences in reporter gene expression when crossed to EGFP or LacZ reporter mice. Line 1 with an estimated 2 copies of the Cdh5-cre transgene was analyzed further.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cdh5-cre)1Nmoc activity also observed in:
cardiovascular system, hemolymphoid system, liver & biliary system, respiratory system
Tissue Information
Mesenchyme Other recombinase alleles with activity in Mesenchyme tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory