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Tg(Fzd10-cre/Esr1*)1Chzh - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Fzd10-cre/Esr1*)1Chzh
transgene insertion 1, Chunjie Zhao
Driver: Fzd10
Type: Transgenic (Inducible, Recombinase)
Inducer: Induced by tamoxifen
Synonym: Frizzled10-CreERTM, Tg(Fzd10-cre/ERT2)1Chzh
Molecular description: The transgenic construct contained a 6.7 kb fragment upstream of the transcriptional start site of the mouse Fzd10 gene followed by a CreERTM cassette carrying a polyA sequence. This construct was injected into fertilized oocytes with five transgenic founders obtained. Expression analysis showed that 3 lines exhibited expression patterns similar to a previously characterized transgenic Fzd10 reporter mouse line. One line was picked for further characterization.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Fzd10-cre/Esr1*)1Chzh activity also observed in:
embryo-other
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:146827 Fig. 1 J:146827 Fig. 2 J:146827 Fig. 3 J:146827 Fig. 4 J:146827 Fig. S1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory