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Tg(Chat-cre)GM24Gsat - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Chat-cre)GM24Gsat
transgene insertion GM24, GENSAT Project at Rockefeller University 		Driver: Chat
Type: Transgenic (Recombinase)
Synonym: GM24, Tg(Chat-cre)24Gsat
Molecular description: A Cre-expression cassette, followed by a polyadenylation sequence to terminate transcription of the fusion transcript immediately after the recombinase gene, was inserted into a BAC vector at the initiating ATG codon in the first coding exon of the gene. The Cre expression pattern matches adult Chat gene expression (all cholinergic neurons) and is limited to motor neurons, with minimal expression in forebrain structures.
Collection: GENSAT
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Chat-cre)GM24Gsat activity also observed in:
head, sensory organs
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:145110 Fig. 1 J:145110 Fig. S4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 33 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory