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Hprttm16(Ple167-EGFP/cre)Ems - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Hprttm16(Ple167-EGFP/cre)Ems
hypoxanthine guanine phosphoribosyl transferase; targeted mutation 16, Elizabeth M Simpson
Driver: POGZ
Type: Targeted (Recombinase)
Synonym: Hprt1tm16(mEMS681)Ems, Hprt1tm16(Ple167-EGFPcre;mEMS681)Ems, NLS-EGFP/cre, Ple167, POGZ-A-EGFP/cre
Molecular description: The Ple167-EGFP/cre transgene (pEMS1091) was designed with the 1200 bp Ple167 minipromoter (POGZ-A; derived from a portion of the promoter of the POGZ gene from the Pogo transposable element with ZNF domain (POGZ) gene) upstream of a minimal F5 mutant-frt site, an EGFP/Cre fusion protein (enhanced green fluorescent protein (with mutated stop) and Cre recombinase), a nuclear localization signal, a second minimal frt site, an SV40 early polyA signal, and a human HPRT complementary sequence (containing exon1, intron1, exon2, and part of intron2). This construct was targeted as a single copy knockin to the Hprtb-m3 mutant locus on the X chromosome.
Collection: Pleiades Promoter Project
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 4 lines available
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
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J:164356 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory