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Hprttm9(Ple178-EGFP/cre)Ems - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Hprttm9(Ple178-EGFP/cre)Ems
hypoxanthine guanine phosphoribosyl transferase; targeted mutation 9, Elizabeth M Simpson
Driver: RGS16
Type: Targeted (Recombinase)
Synonym: Hprt1tm9(mEMS756)Ems, Hprt1tm9(Ple178-EGFPcre;mEMS756)Ems, RGS16-D-EFGP/cre
Molecular description: The Ple178-EGFPCre transgene (pEMS1090) was designed with the 864 bp Ple178 minipromoter (RGS16-D; derived from an intronic candidate regulatory region and a subsection of the human regulator of G-protein signaling 16 (RGS16) promoter) upstream of a minimal F5 mutant-frt site, an EGFP/Cre fusion protein (enhanced green fluorescent protein (with mutated stop) and Cre recombinase), a nuclear localization signal, a second minimal frt site, an SV40 early polyA signal, and a human HPRT complementary sequence (containing exon1, intron1, exon2, and part of intron2).
Collection: Pleiades Promoter Project
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 4 lines available
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
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J:164356 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory