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Allele Information
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Allele:
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Twist2tm1.1(cre)Dor
twist basic helix-loop-helix transcription factor 2;
targeted mutation 1.1, David M Ornitz
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Driver: Twist2
Type: Targeted (knock-in)
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Synonym:
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Molecular description:
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A targeting vector was designed to replace the first exon of the targeted gene with a cre cDNA sequence and an frt-flanked PGK-neo cassette. The construct was electroporated into 129X1/SvJ-derived RW4 embryonic stem (ES) cells. Chimeric mice were bred to generate mutant mice. Mutant mice were then bred to FLPe mice (C57 genetic background) to remove the selection cassette.
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Find mice (IMSR):
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Mouse Strains:
1 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Twist2tm1.1(cre)Dor activity also observed in:
adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
cavities and their linings,
embryo-other,
endocrine system,
extraembryonic component,
hemolymphoid system,
integumental system,
limbs,
liver and biliary system,
mesenchyme,
muscle,
nervous system,
postnatal-other,
renal and urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system
(less)
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Tissue Information
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Tail
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Other recombinase alleles with activity in Tail tissues:
Calb2tm1(cre)Zjh,
En1tm2(cre)Wrst,
Myf5tm3(cre)Sor,
Omptm4(cre)Mom,
Pax3tm1(cre)Joe,
Six1tm1(cre,ALPP)Xli,
Tg(Cdh5-cre)7Mlia,
Tg(CDX2-cre*)189Erf,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Dll1-cre)33Dchp,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp4-cre)1Rev,
Tgfb3tm1(cre)Vk,
Tg(Foxa3-cre)1Khk,
Tg(GFAP-cre)25Mes,
Tg(Hhex-cre,-GFP)1Ksz,
Tg(Hoxb3-cre)1Pkht,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Ins2-cre)25Mgn,
Tg(Mef2c-cre)1Blk,
Tg(Nodal*-cre)#Mku,
Tg(Pax3-cre)1Joe,
Tg(Pcp2-cre)1Amc,
Tg(Pitx3-cre/ERT2)1Ydq,
Tg(Prph1-cre)35Dmd,
Tg(Sim1-cre)1Lowl,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jomm,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Thy1-cre)1Vln,
Tg(Ure2-cre)1Jlr,
Tg(Wnt1-cre)11Rth,
Tg(Zp3-cre)3Mrt
(less)
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Images
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J:184579
Fig. Twist2 Embryo 1 E15.5
J:184579
Fig. Twist2 Embryo 2 E15.5
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools