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Allele Information
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Allele:
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Twist2tm1.1(cre)Dor
twist basic helix-loop-helix transcription factor 2;
targeted mutation 1.1, David M Ornitz
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Driver: Twist2
Type: Targeted (knock-in)
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Synonym:
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Molecular description:
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A targeting vector was designed to replace the first exon of the targeted gene with a cre cDNA sequence and an frt-flanked PGK-neo cassette. The construct was electroporated into 129X1/SvJ-derived RW4 embryonic stem (ES) cells. Chimeric mice were bred to generate mutant mice. Mutant mice were then bred to FLPe mice (C57 genetic background) to remove the selection cassette.
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Find mice (IMSR):
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Mouse Strains:
1 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Twist2tm1.1(cre)Dor activity also observed in:
adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
cavities and their linings,
embryo-other,
endocrine system,
extraembryonic component,
hemolymphoid system,
integumental system,
limbs,
liver and biliary system,
mesenchyme,
muscle,
nervous system,
postnatal-other,
renal and urinary system,
reproductive system,
respiratory system,
sensory organs,
tail
(less)
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Tissue Information
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Skeletal System
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Other recombinase alleles with activity in Skeletal System tissues:
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Ctsktm1(cre)Ska,
En1tm2(cre)Wrst,
Myf5tm1.1(cre)Mrc,
Myf5tm3(cre)Sor,
Nkx3-2tm3.1(cre)Tlu,
Nkx3-2tm4.1(cre)Tlu,
Omptm4(cre)Mom,
Pax3tm1(cre)Joe,
Ssttm2.1(cre)Zjh,
Tg(BGLAP-cre)1Clem,
Tg(CD2-cre)4Kio,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Col1a1-cre)1Bek,
Tg(Col1a1-cre)1Kry,
Tg(Col1a1-cre)2Bek,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a1-cre/Esr1*)1Mis,
Tg(Col1a1-cre)#Xya,
Tg(Col1a2-cre)23Angl,
Tg(Col1a2-cre/ERT)7Cpd,
Tg(Col2a1-cre)1Asz,
Tg(Col2a1-cre)1Bhr,
Tg(Col2a1-cre/ERT2)1Dic,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(dlx6a-cre)1Mekk,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp4-cre)1Rev,
Tg(GFAP-cre)25Mes,
Tg(Hand2-cre)7-1Clou,
Tg(Hspa2-cre)1Eddy,
Tg(Ins2-cre)25Mgn,
Tg(Kdr-cre)15962Brei,
Tg(mI56i-cre)6-2Clou,
Tg(Nes-cre)1Atp,
Tg(Pcp2-cre)1Amc,
Tg(Pf4-cre)Q3Rsko,
Tg(S100b-EGFP/cre/ERT2)22Amc,
Tg(Sim1-cre)1Lowl,
Tg(Tagln-cre)1Her,
Tg(Thy1-cre)1Vln
(less)
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Images
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J:184579
Fig. Twist2 Embryo 1 E15.5
J:184579
Fig. Twist2 Embryo 2 E15.5
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools