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Allele Information
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Allele:
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Twist2tm1.1(cre)Dor
twist basic helix-loop-helix transcription factor 2;
targeted mutation 1.1, David M Ornitz
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Driver: Twist2
Type: Targeted (knock-in)
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Synonym:
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Molecular description:
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A targeting vector was designed to replace the first exon of the targeted gene with a cre cDNA sequence and an frt-flanked PGK-neo cassette. The construct was electroporated into 129X1/SvJ-derived RW4 embryonic stem (ES) cells. Chimeric mice were bred to generate mutant mice. Mutant mice were then bred to FLPe mice (C57 genetic background) to remove the selection cassette.
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Find mice (IMSR):
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Mouse Strains:
1 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Twist2tm1.1(cre)Dor activity also observed in:
adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
cavities and their linings,
embryo-other,
endocrine system,
extraembryonic component,
hemolymphoid system,
integumental system,
limbs,
liver and biliary system,
mesenchyme,
muscle,
nervous system,
renal and urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system,
tail
(less)
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Tissue Information
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Postnatal-other
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Other recombinase alleles with activity in Postnatal-other tissues:
Acantm1(cre/ERT2)Crm,
Corttm1(cre)Zjh,
Ctsktm1(cre)Ska,
Dlx5tm1(cre/ERT2)Zjh,
En1tm2(cre)Wrst,
Gad2tm2(cre)Zjh,
Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn,
HhatTg(TFAP2A-cre)1Will,
Hprttm1(cre)Mnn,
Hsd11b2tm1(cre)Anft,
Myf5tm1.1(cre)Mrc,
Myf5tm3(cre)Sor,
Omptm4(cre)Mom,
Pax3tm1(cre)Joe,
Shhtm1(EGFP/cre)Cjt,
Slc6a3tm1.1(cre)Bkmn,
Ssttm2.1(cre)Zjh,
Tg(Acp5-cre)3Rda,
Tg(Acp5-cre)4Rda,
Tg(Acvrl1-cre)B1Spo,
Tg(Acvrl1-cre)L1Spo,
Tg(Bglap2-cre)2Kry,
Tg(CAG-cre)2Osb,
Tg(CD2-cre)4Kio,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Col10a1-cre)1427Vdm,
Tg(Col10a1-cre)1Xya,
Tg(Col11a2-cre)4Nhzi,
Tg(Col1a1-cre)1Bek,
Tg(Col1a1-cre)1Kry,
Tg(Col1a1-cre)2Bek,
Tg(Col1a1-cre/ERT2)1Crm,
Tg(Col1a2-cre/ERT)7Cpd,
Tg(Col2a1-cre)1Bhr,
Tg(Col2a1-cre)1Star,
Tg(Col2a1-cre)1Xya,
Tg(Col2a1-cre/ERT)1Flng,
Tg(Col2a1-cre/ERT2)1Dic,
Tg(Col2a1-cre/ERT)KA3Smac,
Tg(Col2a1-rtTA,tetO-cre)22Pjro,
Tg(Col6a1-cre)1Gkl,
Tg(Csrp1-cre)1Sjc,
Tg(Ctsk-cre)1Rda,
Tg(Ctsk-cre)8Rda,
Tg(Ddx4-cre)1Dcas,
Tg(Dmp1-cre)1Jqfe,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp4-cre)1Rev,
Tg(GFAP-cre)25Mes,
Tg(Grik4-cre)G32-4Stl,
Tg(Ins2-cre)25Mgn,
Tg(Itgam-cre)AJva,
Tg(Itgax-cre)1-1Reiz,
Tg(KRT14-cre)1Efu,
Tg(Mef2c-cre)1Blk,
Tg(Mitf-cre)710-59Gsb,
Tg(Mitf-cre)7114Gsb,
Tg(Pax3-cre)2Joe,
Tg(Pcp2-cre)1Amc,
Tg(Pf4-cre)Q3Rsko,
Tg(Postn-cre)1Sjc,
Tg(Pres-cre)1Jnz,
Tg(rtetR-TetO-cre)40Mhz,
Tg(Runx2-icre)1Jtuc,
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc,
Tg(Tagln-cre)1Her,
Tg(Thy1-cre)1Vln,
Tg(TSPY-cre)33aYfcl,
Twist2tm1(cre)Dor
(less)
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Images
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J:184579
Fig. Twist2 Bone P7
J:90391
Fig. 1
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools