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Twist2tm1.1(cre)Dor - Endocrine System
Recombinase Activity Detail
Allele Information
twist basic helix-loop-helix transcription factor 2; targeted mutation 1.1, David M Ornitz
Driver: Twist2
Type: Targeted (Recombinase)
Synonym: dermo-1Cre
Molecular description: A targeting vector was designed to replace the first exon of the targeted gene with a cre cDNA sequence and an frt-flanked PGK-neo cassette. The construct was electroporated into 129X1/SvJ-derived RW4 embryonic stem (ES) cells. Chimeric mice were bred to generate mutant mice. Mutant mice were then bred to FLPe mice (C57 genetic background) to remove the selection cassette.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Twist2tm1.1(cre)Dor activity also observed in:
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
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J:184579 Full image
Fig. Twist2 Adrenal P56
J:184579 Full image
Fig. Twist2 Adrenal P7
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory