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Allele Information
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Allele:
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Twist2tm1.1(cre)Dor
twist basic helix-loop-helix transcription factor 2;
targeted mutation 1.1, David M Ornitz
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Driver: Twist2
Type: Targeted (knock-in)
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Synonym:
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Molecular description:
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A targeting vector was designed to replace the first exon of the targeted gene with a cre cDNA sequence and an frt-flanked PGK-neo cassette. The construct was electroporated into 129X1/SvJ-derived RW4 embryonic stem (ES) cells. Chimeric mice were bred to generate mutant mice. Mutant mice were then bred to FLPe mice (C57 genetic background) to remove the selection cassette.
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Find mice (IMSR):
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Mouse Strains:
1 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Twist2tm1.1(cre)Dor activity also observed in:
adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
embryo-other,
endocrine system,
extraembryonic component,
hemolymphoid system,
integumental system,
limbs,
liver and biliary system,
mesenchyme,
muscle,
nervous system,
postnatal-other,
renal and urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system,
tail
(less)
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Tissue Information
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Cavities And Their Linings
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Other recombinase alleles with activity in Cavities And Their Linings tissues:
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
En1tm2(cre)Wrst,
Gt(ROSA)26Sortm1(cre/ERT)Brn,
Myf5tm3(cre)Sor,
Pax3tm1(cre)Joe,
Tg(Cdh5-cre)7Mlia,
Tg(dlx6a-cre)1Mekk,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp4-cre)1Rev,
Tg(GATA5-cre)1Krc,
Tg(Grik4-cre)G32-4Stl,
Tg(Hspa2-cre)1Eddy,
Tg(KRT14-cre)1Amc,
Tg(Nes-cre)1Atp,
Tg(Pf4-cre)Q3Rsko,
Tg(Sim1-cre)1Lowl,
Tg(Tagln-cre)1Her,
Tg(Thy1-cre)1Vln,
Tg(Wnt1-cre)11Rth
(less)
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Images
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J:184579 Fig. Twist2 Embryo 1 E15.5
J:184579 Fig. Twist2 Embryo 2 E15.5
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Recombinase Activity
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Click heading to resort table.
Assays
Genotypic Background
Result Notes
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References
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