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Tg(Cryaa-cre,Tyr)39Mlr - Embryo-other
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cryaa-cre,Tyr)39Mlr
transgene insertion 39, Mike Robinson 		Driver: Cryaa
Type: Transgenic (Recombinase)
Synonym: CPV2/Cre, MLR39-Cre
Molecular description: A cre recombinase gene was driven by an alpha A crystallin promoter consisting of -282/+43 of the mouse Cryaa gene. Seven founder lines were generated using this construct, which in this line was coinjected with a tyrosinase minigene. Line 39 has expression of the transgene in lens fiber cells but not in the surrounding lens epithelium. Ectopic expression of the transgene was also detected in the retinal pigment epithelium and in the ciliary bodies of the eye.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cryaa-cre,Tyr)39Mlr activity also observed in:
head, sensory organs
Tissue Information
Embryo-other Other recombinase alleles with activity in Embryo-other tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory