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Tg(Tek-cre)2352Rwng - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tek-cre)2352Rwng
transgene insertion 2352, Rong Wang 		Driver: Tek
Type: Transgenic (Cre/Flp)
Synonym: Tg(Tek-cre)1Lfr, Tie2Cre, tie2-cre, Tg(Tie2-Cre)2352
Molecular description: A transgenic construct containing sequence encoding cre under the control of of the mouse Tek, endothelial-specific receptor tyrosine kinase (also known as Tie2), promoter was introduced into FVB/N donor eggs. Founder line 2352 was subsequently established. Cre recombinase expression is detected in most endothelial cells and blood islands of the extraembryonic mesoderm by embryonic day (E)7.5, in the dorsal aorta by E8.5 and is very strong in head vasculature by E9.
Find mice (IMSR): Mouse Strains: 1 lines available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tek-cre)2352Rwng activity also observed in:
extraembryonic component
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Images
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J:104401
Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory