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Allele Information
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Allele:
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Hcn4tm1(cre/ERT2)Anlu
hyperpolarization-activated, cyclic nucleotide-gated K+ 4;
targeted mutation 1, Andreas Ludwig
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Driver: Hcn4
Type: Targeted (knock-in)
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Inducer:
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induced by tamoxifen
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Synonym:
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HCN4-KiT, Hcn4tm1(cre/ESR1)Anlu
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Molecular description:
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A cre/ERT2 fusion gene and a neo cassette were inserted into exon 1 downstream of the translation initiation codon. Expression is tamoxifen inducible and localized to the superior vena cava in the proximity of the right atrial appendage and the aorta, specifically in the sinoatrial and atrioventricular nodes.
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Find mice (IMSR):
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Mouse Strains:
0 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Hcn4tm1(cre/ERT2)Anlu activity also observed in:
cardiovascular system
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Tissue Information
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Muscle
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Other recombinase alleles with activity in Muscle tissues:
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
En1tm2(cre)Wrst,
Gad2tm2(cre)Zjh,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
HhatTg(TFAP2A-cre)1Will,
Hprttm1(cre)Mnn,
Hsd11b2tm1(cre)Anft,
Isl1tm1(cre/Esr1*)Krc,
Isl1tm1(cre)Tmj,
Kdrtm1(cre)Sato,
Mnx1tm4(cre)Tmj,
Myf5tm1.1(cre)Mrc,
Myf5tm1(cre)Mrc,
Myf5tm3(cre)Sor,
Myf6tm1(cre)Mrc,
Myf6tm2(cre)Mrc,
Omptm4(cre)Mom,
Pax3tm1(cre)Joe,
Pvalbtm1(cre)Arbr,
Shhtm1(EGFP/cre)Cjt,
Taglntm2(cre)Yec,
Tg(ACTA1-cre)1Mll,
Tg(ACTA1-cre)79Jme,
Tg(ACTA1-rtTA,tetO-cre)102Monk,
Tg(Acta2-cre/ERT2)12Pcn,
Tg(Acta2-cre/ERT2)51Pcn,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)86Lbgn,
Tg(CD2-cre)4Kio,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Cga-cre)3Sac,
Tg(CMV-cre)1Cgn,
Tg(Col6a1-cre)1Gkl,
Tg(Csf1r-icre)1Jwp,
Tg(Csrp1-cre)1Sjc,
Tg(Cyp1a1-cre)1Dwi,
Tg(dlx6a-cre)1Mekk,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp4-cre)1Rev,
Tg(Gata1-cre)1Sho,
Tg(Grik4-cre)G32-4Stl,
Tg(Hoxb8-cre)1403Uze,
Tg(Hspa2-cre)1Eddy,
Tg(Ins2-cre)25Mgn,
Tg(Itgax-cre)1-1Reiz,
Tg(Mef2c-cre)1Blk,
Tg(Mef2c-cre)2Blk,
Tg(Myh11-cre)5013Gko,
Tg(Myh6-cre)2182Mds,
Tg(Myhc-cre)1Xya,
Tg(Myl1-cre)13Nros,
Tg(Nes-cre)1Kln,
Tg(Pcp2-cre)1Amc,
Tg(Pcp2-cre)2Mpin,
Tg(Pdgfb-icre/ERT2)1Frut,
Tg(Pf4-cre)Q3Rsko,
Tg(Pitx3-cre/ERT2)1Ydq,
Tg(Prrx1-cre)1Cjt,
Tg(rtetR-tetO-cre)1Mhz,
Tg(Sim1-cre)1Lowl,
Tg(Tagln-cre)1Her,
Tg(Tagln-cre)1Jjl,
Tg(Tal1-cre/ERT)1Jrg,
Tg(Tal1-cre/ERT)42-056Jrg,
Tg(Tbx1-cre)1Joe,
Tg(Tek-cre)1Ywa,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre/ERT2)1Soff,
Tg(Thy1-cre)1Vln,
Tg(Vav1-cre)1Awr,
Tg(Vav1-cre)8Cgp,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt1-cre)11Rth,
Twist2tm1.1(cre)Dor,
Viptm1(cre)Zjh
(less)
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools
