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Hcn4tm1(cre/ERT2)Anlu - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Hcn4tm1(cre/ERT2)Anlu
hyperpolarization-activated, cyclic nucleotide-gated K+ 4; targeted mutation 1, Andreas Ludwig
Driver: Hcn4
Type: Targeted (Inducible, Recombinase)
Inducer: induced by tamoxifen
Synonym: HCN4-KiT, HCN4KiT-Cre, Hcn4tm1(cre/ESR1)Anlu
Molecular description: A cre/ERT2 fusion gene and a neo cassette were inserted into exon 1 downstream of the translation initiation codon. Expression is tamoxifen inducible and localized to the superior vena cava in the proximity of the right atrial appendage and the aorta, specifically in the sinoatrial and atrioventricular nodes.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory