About   Help   FAQ
Gt(ROSA)26Sortm2(icre/ERT2)Jphe - Integumental System
Recombinase Activity Detail
Allele Information
gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Jean-Paul Herman
Driver: Gt(ROSA)26Sor
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Cre2ERT2, ERT2-iCre-ERT2, Gt(ROSA)26Sortm2(cre/ESR1)Jphe
Molecular description: A humanized cre gene flanked by 2 tamoxifen-binding domains (ERT2-icre-ERT2) and followed by an frt-flanked hygro cassette was knocked into the locus. Inducible cre expression is present in all cells following treatment with tamoxifen with only the brain exhibiting decresed expression levels.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Gt(ROSA)26Sortm2(icre/ERT2)Jphe activity also observed in:
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:135150 Fig. 3
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
All for this allele: 1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.03
The Jackson Laboratory