About   Help   FAQ
Tg(Nkx2-1-cre)2Sand - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Nkx2-1-cre)2Sand
transgene insertion 2, Stewart Anderson
Driver: Nkx2-1
Type: Transgenic (Recombinase)
Synonym: Nkx2-1BACCre, Nkx2.1-cre, NKX2.1Cre, Tg(Nkx2-1-cre)1Qixu, Tg(Nkx2-1-cre)2Qixu, Ttf-1Cre
Molecular description: A mouse BAC clone containing the Nkx2-1 gene was engineered to express cre recombinase. Fifteen base pairs at the 5'end of exon 2 of the Nkx2-1 gene were replaced with a cre-poly(A) construct. The mutated BAC clone was then used to generate transgenic mice. This construct is expressed in brain, thyroid, pituitary, and lung, with telecephalic expression first detectable at E10.5.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Nkx2-1-cre)2Sand activity also observed in:
mesenchyme, nervous system, respiratory system
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:184579 Full image
Fig. Nkx2-1 E10.5 Embryo 3
J:184579 Full image
Fig. Nkx2-1 E15.5 Embryo 1
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 34 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory