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Tg(Nes-cre/ERT2)KEisc - Nervous System
Recombinase Activity Detail
Allele Information
transgene insertion K, Amelia Eisch
Driver: Nes
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Nestin-CreERT2, Tg(Nes-cre/ERT2)KJejo, Tg(Nes-cre/ESR1)KJejo, Tg(Nes-cre)KJejo
Molecular description: The Nestin-cre/ERT2 transgene was designed with the rat nestin (Nes) promoter driving expression of a CreERT2 fusion gene (cre/ERT2; Cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain). The transgene was microinjected into fertilized C57BL/6J oocytes, and line K was established.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
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J:117032 Fig. 4 J:117032 Fig. 5 J:117032 Fig. S1
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 36 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory