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Gt(ROSA)26Sortm3(phiC31*)Sor - Embryo-other
Recombinase Activity Detail
Allele Information
Allele:
Gt(ROSA)26Sortm3(phiC31*)Sor
gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Philippe Soriano 		Driver: Gt(ROSA)26Sor
Type: Targeted (knock-in)
Synonym: R26phiC31o
Molecular description: A targeting construct with the SA-PhiC31opA-PGKneopA cassette, which contains the mouse codon-optimized site-specific recombinase PhiC31o sequence (with a C-terminal SV40 nuclear localization signal) driven by the phosphoglycerate kinase 1 (PGK) promoter, and bovine growth hormone polyadenylation (bpA) sequence was inserted into the Gt(ROSA)26Sor locus. Flp-mediated recombination removes the neo cassette. PhiC31o-mediated recombination in mice carrying containing a sequence of interest flanked by attB and attP sites results in tissue-specific deletion of the targeted sequence.
Find mice (IMSR): Mouse Strains: 2 lines available       Cell Lines: 0 lines available
Tissue Information
Embryo-other Other recombinase alleles with activity in Embryo-other tissues:
Images
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J:128069
Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/22/2013
MGI 5.13 		The Jackson Laboratory