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Allele Information
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Allele:
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Tg(Pf4-cre)Q3Rsko
transgene insertion Q3, Radek C Skoda
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Driver: Pf4
Type: Transgenic (Cre/Flp)
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Synonym:
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Tg(Cxcl4-cre)Q3Rsko, Pf4-Cre
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Molecular description:
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A transgene was created from a BAC where cre-recombinase is driven by the Cxcl4 (Platelet factor 4) promoter. This transgene also contains the Cxcl3, Cxcl5, Ppbp, and Cxcl15 genes. This line has one copy of the transgene inserted with expression restricted to megakaryocytes and platelets, as demonstrated by RT-PCR and Western blotting.
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Find mice (IMSR):
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Mouse Strains:
1 lines available
Cell Lines:
0 lines available
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Additional Tissues:
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Tg(Pf4-cre)Q3Rsko activity also observed in:
adipose tissue,
alimentary system,
cardiovascular system,
cavities and their linings,
endocrine system,
integumental system,
limbs,
liver and biliary system,
mesenchyme,
muscle,
nervous system,
postnatal-other,
renal and urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system
(less)
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Tissue Information
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Hemolymphoid System
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Other recombinase alleles with activity in Hemolymphoid System tissues:
Airetm3(cre)Mmat,
Calb2tm1(cre)Zjh,
Ccktm1.1(cre)Zjh,
Cd19tm1(cre)Cgn,
Crhtm1(cre)Zjh,
Emx1tm1(cre)Krj,
Fgf16tm1.1(cre)Sms,
Foxn1tm3(cre)Nrm,
Gja10tm2.1(cre)Kwi,
Gt(ROSA)26Sortm1.1(cre)Jphe,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Hprttm1(cre)Mnn,
Ighg1tm1(IRES-cre)Cgn,
Lyz2tm1(cre)Ifo,
Mcm2tm1(cre/ERT2)Scpr,
Mnx1tm4(cre)Tmj,
Myf5tm3(cre)Sor,
Neurod6tm1(cre)Kan,
Pax3tm1(cre)Joe,
Pvalbtm1(cre)Arbr,
Shhtm1(EGFP/cre)Cjt,
Slc6a3tm1.1(cre)Bkmn,
Sox17tm1(icre)Heli,
Tg(Acp5-cre)3Rda,
Tg(ACTB-cre)1Tes,
Tg(Aicda-cre)9Mbu,
Tg(Aire-cre)1Mnt,
Tg(Aire-cre)410-5Mmat,
Tg(CD2-cre)4Kio,
Tg(Cdh5-cre)1Nmoc,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Chst4-cre)1Hkwa,
Tg(Cma1-cre)6Thhe,
Tg(CMV-cre)1Cgn,
Tg(CMV-cre)1Nagy,
Tg(Col1a2-cre)23Angl,
Tg(Cr2-cre)3Cgn,
Tg(Csf1r-icre)1Jwp,
Tg(Cyp17a1-cre)ACmk,
Tg(EIIa-cre)C5379Lmgd,
Tg(Fabp4-cre)1Rev,
Tg(Gata1-cre)1Sho,
Tg(GFAP-cre)25Mes,
Tg(Grik4-cre)G32-4Stl,
Tg(GZMB-cre)1Jcb,
Tg(H2-Ead-cre)158Jcb,
Tg(HBB-cre)12Kpe,
Tg(HBB-cre)27038Kpe,
Tg(HBB-cre)27053Kpe,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Il7-cre)CRche,
Tg(Itga2b-cre)AParl,
Tg(Itga2b-cre)NE1/21Emam,
Tg(ITGAM-cre)2781Gkl,
Tg(Itgax-cre)1-1Reiz,
Tg(Kdr-cre)15962Brei,
Tg(KRT14-cre)1Amc,
Tg(KRT14-cre)1Cgn,
Tg(KRT14-cre)8Brn,
Tg(KRT5-cre/ERT)ICmch,
Tg(KRT5-cre/ERT)SCmch,
Tg(Lck-cre)548Jxm,
Tg(MMTV-cre)1Mam,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)29-4Her,
Tg(Myh11-cre/ERT2)1Soff,
Tg(Nes-cre)1Atp,
Tg(Nes-cre)1Kln,
Tg(Neurog3-cre)C1Able,
Tg(Nr5a1-cre)2Klp,
Tg(Nr5a1-cre)2Lowl,
Tg(Pcp2-cre)1Amc,
Tg(Pdgfb-icre/ERT2)1Frut,
Tg(Plp1-cre/ERT)3Pop,
Tg(Sim1-cre)1Lowl,
Tg(Sox10-cre)1Wdr,
Tg(Tagln-cre)1Her,
Tg(Tek-cre)12Flv,
Tg(Tek-cre)1Arnd,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre/ERT2)1Arnd,
Tg(Tek-cre/ERT2)1Soff,
Tg(Thy1-cre)1Vln,
Tg(Vav1-cre)1Cgp,
Tg(Vav1-cre)1Graf,
Tg(Vav1-cre)8Cgp,
Tg(Vav1-cre)A2Kio,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt1-cre)11Rth,
Tg(Zp3-cre)3Mrt,
Twist2tm1.1(cre)Dor
(less)
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Images
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Reset Images
J:184579
Fig. Pf4 Bone Adult
J:184579
Fig. Pf4 Bone Marrow P7
J:184579
Fig. Pf4 Spleen Adult
J:184579
Fig. Pf4 Spleen P7
J:184579
Fig. Pf4 Thymus Adult
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Recombinase Activity
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Click heading to resort table.
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References
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Analysis Tools