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Tg(Pf4-icre)Q3Rsko - Hemolymphoid System
Recombinase Activity Detail
Allele Information
transgene insertion Q3, Radek C Skoda
Driver: Pf4
Type: Transgenic (Recombinase)
Synonym: (Pf4)-Cre, Pf4-Cre, Tg(Cxcl4-cre)Q3Rsko, Tg(Pf4-cre)Q3Rsko
Molecular description: A transgene was created from a BAC where cre-recombinase is driven by the Cxcl4 (Platelet factor 4) promoter. This transgene also contains the Cxcl3, Cxcl5, Ppbp, and Cxcl15 genes. This line has one copy of the transgene inserted with expression restricted to megakaryocytes and platelets, as demonstrated by RT-PCR and Western blotting.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pf4-icre)Q3Rsko activity also observed in:
Tissue Information
Hemolymphoid System Other recombinase alleles with activity in Hemolymphoid System tissues:
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Fig. Pf4 Bone Marrow P7
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Fig. Pf4 Bone P56
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Fig. Pf4 Spleen P56
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Fig. Pf4 Spleen P7
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Fig. Pf4 Thymus P56
Recombinase Activity
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Assays Genotypic Background Result Notes  
All for this allele: 95 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory