|
|
|
Allele Information
|
|
Allele:
|
Tg(Pf4-cre)Q3Rsko
transgene insertion Q3, Radek C Skoda
|
Driver: Pf4
Type: Transgenic (Cre/Flp)
|
|
|
Synonym:
|
Tg(Cxcl4-cre)Q3Rsko, Pf4-Cre
|
|
Molecular description:
|
A transgene was created from a BAC where cre-recombinase is driven by the Cxcl4 (Platelet factor 4) promoter. This transgene also contains the Cxcl3, Cxcl5, Ppbp, and Cxcl15 genes. This line has one copy of the transgene inserted with expression restricted to megakaryocytes and platelets, as demonstrated by RT-PCR and Western blotting.
|
|
Find mice (IMSR):
|
Mouse Strains:
1 lines available
Cell Lines:
0 lines available
|
|
Additional Tissues:
|
Tg(Pf4-cre)Q3Rsko activity also observed in:
adipose tissue,
alimentary system,
cardiovascular system,
cavities and their linings,
hemolymphoid system,
integumental system,
limbs,
liver and biliary system,
mesenchyme,
muscle,
nervous system,
postnatal-other,
renal and urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system
(less)
|
|
|
Tissue Information
|
|
Endocrine System
|
Other recombinase alleles with activity in Endocrine System tissues:
1700009P17Riktm1.1(icre)Heli,
Ccktm1.1(cre)Zjh,
Cpa1tm1(cre/ERT2)Dam,
Fgf16tm1.1(cre)Sms,
Gt(ROSA)26Sortm1.1(cre)Jphe,
Gt(ROSA)26Sortm1(cre/ERT2)Tyj,
Gt(ROSA)26Sortm1(cre/ERT)Brn,
Gt(ROSA)26Sortm2(icre/ERT2)Jphe,
Hnf4atm1(cre)Sdv,
Hprttm1(cre)Mnn,
Krt19tm1(cre/ERT)Ggu,
Mnx1tm4(cre)Tmj,
Myf5tm3(cre)Sor,
Notch1tm3(cre)Rko,
Omptm4(cre)Mom,
Pax3tm1(cre)Joe,
Ptf1atm1.1(cre)Cvw,
Shhtm1(EGFP/cre)Cjt,
Ssttm2.1(cre)Zjh,
Tg(ACTB-cre)1Tes,
Tg(ACTFLPe)9205Dym,
Tg(Adipoq-cre)1Evdr,
Tg(Akr1b7-cre)1Anm,
Tg(Amy2-cre)1Herr,
Tg(CA2-cre)1Subw,
Tg(CA2-cre/Esr1*)1Subw,
Tg(CAG-cre/Esr1*)1Lbe,
Tg(CAG-cre/Esr1*)5Amc,
Tg(CAG-cre/Esr1*)86Lbgn,
Tg(Camk2a-cre)1Nobs,
Tg(Cdh5-cre)7Mlia,
Tg(Cdh5-cre/ERT2)CIVE23Mlia,
Tg(Cga-cre)3Sac,
Tg(CMV-cre)1Cgn,
Tg(Crx-cre)1Tfur,
Tg(Cyp11a1-cre)16Mchu,
Tg(Cyp17a1-cre)ACmk,
Tg(Cyp1a1-cre)1Dwi,
Tg(Cyp1a1-cre/ERT)1Dwi,
Tg(DBH-cre)6-8Koba,
Tg(DBH-cre)9-9Koba,
Tg(Dbh-cre/ERT2)198.1Hroh,
Tg(Dll1-cre)33Dchp,
Tg(EIIa-cre)C5379Lmgd,
Tg(Ela1-cre)16Eps,
Tg(Ela1-cre/ERT2)1Stof,
Tg(Fabp4-cre)1Rev,
Tg(Gcg-cre)1Herr,
Tg(Gcg-cre)1Slib,
Tg(GFAP-cre)25Mes,
Tg(Gh1-cre)1Sac,
Tg(Gh1-cre)bKnmn,
Tg(Ghrhr-cre)3242Lsk,
Tg(Grik4-cre)G32-4Stl,
Tg(Hoxb7-cre)13Amc,
Tg(Hspa2-cre)1Eddy,
Tg(Inha-cre)1Zuk,
Tg(Inha-cre)2Zuk,
Tg(Inha-cre)3Zuk,
Tg(Ins2-cre)23Herr,
Tg(Ins2-cre)25Mgn,
Tg(INS-icre)18Msdr,
Tg(Itgax-cre)1-1Reiz,
Tg(Kdr-cre)15962Brei,
Tg(Lhb-cre)1Sac,
Tg(Mbp-cre)6Gvn,
Tg(Mbp-cre)9Gvn,
Tg(MMTV-cre)4Mam,
Tg(Mx1-cre)1Cgn,
Tg(Nes-cre)1Kln,
Tg(Neurog3-cre)1Dam,
Tg(NEUROG3-cre)1Herr,
Tg(Neurog3-cre)C1Able,
Tg(Neurog3-cre/Esr1*)1Dam,
Tg(Nr5a1-cre)1Kmor,
Tg(Nr5a1-cre)2Klp,
Tg(Nr5a1-cre)2Lowl,
Tg(Nr5a1-cre)7Lowl,
Tg(Nr5a1-cre/ERT2)4Kmor,
Tg(Pax4-cre)1Dam,
Tg(Pax6-cre)1Rilm,
Tg(Pax6-cre,GFP)1Pgr,
Tg(Pcp2-cre)2Mpin,
Tg(Pdx1-cre)1Herr,
Tg(Pdx1-cre)6Cvw,
Tg(Pdx1-cre)89.1Dam,
Tg(Pdx1-cre/Esr1*)35.10Dam,
Tg(Pdx1-cre/Esr1*)35.6Dam,
Tg(Pgk1-cre)1Lni,
Tg(Pitx1-cre)1Rsd,
Tg(Pomc-cre)5Brn,
Tg(Prm-cre)58Og,
Tg(PTH-cre)4167Slib,
Tg(Rarb-cre)1Bhr,
Tg(REN-cre)1Haca,
Tg(Sim1-cre)1Lowl,
Tg(Sycp1-cre)4Min,
Tg(Tagln-cre)1Her,
Tg(Tek-cre)1Arnd,
Tg(Tek-cre)5326Sato,
Tg(Tek-cre/ERT2)1Arnd,
Tg(tetO-cre)1Jaw,
Tg(Tg-cre)1Soff,
Tg(Th-cre)12Mrub,
Tg(Th-cre)1Tmd,
Tg(Thy1-cre)1Vln,
Tg(TPO-cre)1Shk,
Tg(Tyr-cre)1Gfk,
Tg(Vav1-cre)8Cgp,
Tg(Vil-cre)997Gum,
Tg(Wfs1-cre/ERT2)3Aibs,
Tg(Wnt1-cre)11Rth,
Thtm1(cre)Te,
Twist2tm1.1(cre)Dor,
Viptm1(cre)Zjh
(less)
|
|
|
Images
|
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail.
Reset Images
J:184579
Fig. Pf4 Adrenal Adult
J:184579
Fig. Pf4 Pancreas Adult
|
|
Recombinase Activity
|
Click heading to resort table.
|
|
References
|
|
Analysis Tools