Ctsk<tm1(cre)Ska> - Head Recombinase Activity Detail MGI Mouse

Ctsk^tm1(cre)Ska - Head
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Ctsk^tm1(cre)Ska
cathepsin K; targeted mutation 1, Shigeaki Kato

Driver: Ctsk
Type: Targeted (Null/knockout, Recombinase)

Synonym:

Cathepsin K-Cre, CatK^Cre, Ctsk^Cre, CtsKCre

Molecular description:

A cre recombinase gene and a downstream frt-flanked kanamycin/neomycin resistance gene was inserted into the endogenous ATG start site of the gene, replacing the first four exons. Chimeric mice were crossed with a deleter strain to remove the selection cassette. Cre expression in heterozygotes was detected in mature osteoclasts but not osteoblasts when crossed with a tester strain.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Ctsk^tm1(cre)Ska activity also observed in:
reproductive system, skeletal system

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

78 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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